Colchicine For Gout: Gout: Not just for Men
Gout, a form of arthritis that seems to be more common in men than in women, in fact does not discriminate according to gender. Women can suffer from this painful condition, too, especially after the menopause. Some studies even suggest that there is a definite increase in women with gout, particularly among the aging female population. The exact reason for the rise of gout among women remains uncertain. An Increase in age, obesity, alcohol consumption, hypertension, and diuretic use have traditionally been associated with the risk of developing gout among women and men.
- Gout will be more likely to be developed by men (almost 90 percent of individuals diagnosed with gout are male), usually after the age of 40.
- In some cases, women at menopause can be affected by the disease too.
- Gout rarely occurs to children and young adults.
Charcot Joints Occur When to be Able to Sense Deep Pain is Lost or Diminished
As a result of the inability to sense pain, small fractures begin to develop in areas of stress such as the arch of the foot. The normal response to a fracture is swelling and increased blood flow (reflex vasodilatation) to the affected area of bone. The increase in blood flow tends to 'wash away' calcium from the fracture site, resulting in weakening of the bone as well as further fractures. If the normal protective system, pain, stays absent, a cycle of increasing fracture activity begins with progressive fall of the supporting bone.
- Lavine LS, Grodinsky AJ: Current principles review: electrical stimulation of repair of bone.
- J Bone fragments Joint Surg Am 69: 626, 1987
Gout, is not just a disease for men. It is also in increasing numbers of women suffer from gout. Colcrys 0.6 milligrams tablets may be prescribed for prevention and treatment of gout. Check out more gout information at http://www.colchicine.ca/
1966 Eichenholz proposed a group of Charcot joints which is broken down into three distinctive stages. Stage one, or the development stage, shows debris surrounding the joints on xray. Stage one can develop over a period of days to weeks and is radiographic change that occurs in response to unperceived trauma. Stage two is the coalescence stage. In stage two, the bone starts to heal with absorption of debris and healing of large fracture fragments. Stage three, often called the reconstruction or reconstitution stage, note a reduction in bone turn over and reformation of stable bone structure. Stage 0 was added in 1999 by Sella and Barrette to include patients who exhibit clinical symptoms of Charcot arthropathy but have yet to show radiographic changes.
- As the number of women who have gout increases, there are other issues that can also arise.
- For instance, women with gout may be 39% more likely to have a heart attack according to some studies.
- However, the increase in the risk of heart attack for men with gout is far less.
- Differential Diagnosis: The differential diagnosis for this condition should include;
- Arthritis rheumatoid and osteoarthritis Bone tumor Diabetic osteolysis
- Low bone mass ensures that bones have less than most select amounts of calcium and other minerals that make your bones strong.
- As a result of low bone mass, bones become weak and break, or can crack, break more easily.
- Bone fractures often occur from falling or tripping or other common accidents.
- Spine fractures can occur while doing daily activities without any injury.
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- Any problem that contributes to the loss of sensation of the foot may be described as a cause for a Charcot joint.
- Some of those conditions include;
- Pap J, Myerson M, GirardP, et al: Save you with arthrodesis in intractable diabetic neuropathic arthropathy of the foot and ankle.
- J Bone Joint Surg Am 75:1056, 1993
- Gout is considered to have a pronounced hereditary character.
- Research results reveal that some people who suffer from gout have a family history of the disease.
One thing that we do know is that we have a larger aging population than in the past, and it continues to grow. The number of women who develop gout has doubled. Women need to consult with their doctors if they think that they are experiencing the pain of undiscovered gout.. Because it has been traditionally associated with men and getting older, often women are not diagnosed as early as they could have been, postponing treatment. Colcrys 0.6mg tablets may be prescribed for prevention and treatment of gout.
Is Very Important to Control Gout Through the Means of a Proper Diet
It is best to keep away from cigarettes and alcohol, as these factors are known to aggravate the disease. Drink plenty of water in order to facilitate the elimination of excessive uric acid (you should drink around 2 liters of water a day). Lastly, try to avoid a sedentary lifestyle; exercise regularly to keep your body in good shape.
- Gout is known to be a rheumatoid form of arthritis that causes inflammation, intense pain, discomfort and swelling of the affected regions.
- Gout mainly tends to affect the joints, especially those of the lower body limbs, for example toes, heels, ankles, knees.
- In some cases, gout may cause inflammation of the elbows and hand wrists.
- Skin and soft tissue such as muscles and muscles can also be affected by the disease, losing their flexibility and elasticity.
- Banks As, McGlamry ED: Charcot Fott.
- JAPMA 79:213, 1989 Pinzur Ms, Sage R, Stuck R, et al: A treatment algorithm for neuropathic (Charcot) midfoot deformity.
- Foot Ankle 14: 189, 1993
- Obesity is another important factor that leads to the development of gout.
- The organisms of overweight people are likely to produce more uric acid.
- Obesity also increases the risks of injury at the level of the joints.
Surgical procedures for Charcot joints are often challenging not only due to the complexity of this condition but also due to the fact that these patients are usually weak surgical candidates due with other health problems (co-morbidity). Surgical procedure may include reconstruction of the arch and/or joint fusion. Often, surgical procedures are used to return the foot to a shape that can be accommodated by regular base wear. Stage three Charcot deformities often result in lumps, bump as well as unusually shaped feet as a result of bone alterations. Reshaping the base may be used to get rid of a boney prominence on the top or bottom of the foot.
All Arthritides Attribute Pain
Pain patterns may be different depending on the arthritides and the location. Rheumatoid arthritis is normally worse in the morning and related to stiffness, in the early stages, people often have no symptoms after their morning shower. In the aged and children, pain might not be the most important presenting feature, the aged person simply moves less, and the child refuses in order to use the affected appendage.
Nomenclature: reflex vasodilitation - increased blood circulation to an area in response to inflammation Rocker bottom foot - a dominance that forms on the sole or bottom of the foot as a result of the collapse from the arch
- Eichenholtz SN: Charcot Joints, Charles C.
- Thomas, Springfield, Il 1966 Giurini JM: Applications and also use of in-shoe orthoses in the conservative management of Charcot foot deformity.
- Clin Podiatric Med Surg 11: 271, 1994
Grady, J.F., et al: The use of electrostimulation in the treatment of diabetic neuroarthropathy J. Am. Podiatric Med. Assoc. 90(6): 287-294, 2000 Sinha, S., Munichoodappa, C.S., Kozak, G.P: Neuroarthropathy Charcot Joints) in diabetes mellitus. Medicine (Baltimore)
Some Facts Surrounding the Probability of Developing Gout Show Consistency
Men between the ages of 40 and 50 appear to be the most notable candidates. Women rarely show symptoms before menopause. Children and young adults are even less likely to be stricken with this painful disease. Heredity affects whether a person develops gout. Having a genetic predisposition accounts for about 18% of the cases.
- Medications that could be a contributing cause of Charcot joints include;
- Injectable and systemic use of steroids Phenylbutazone Indomethacin Vincristine
- By striving at the root of the problem and relieving the pain, try Nana Flex Or NanaFlex Cream .
- The anti-inflammatory natural oils in this blend are aimed at blocking the enzymes that elevate leading to arthritis pain and inflammation.
- And also this improves the flexibility of the affected joint.
Fracture Gout Idiopathic edema Lymphedema Pseudogout Septic arthritis (infected joint) Soft tissue tumor Additional references include;
- Cleveland M: Surgical fusion of volatile joints due to neuropathic disturbance.
- Am J Surg 43: 580, 1939 Wilson M : Charcot foot osteoarthropathy in diabetes mellitus.
- Mil Med 156: 563, 1991
Arthritis is a Joint Disorder Causing Inflammation
A joint is an area of the body where two different bones meet. A shared functions to move the body parts connecting by its bones. Arthritis means inflammation of one or more joints. Arthritic diseases consist of rheumatoid arthritis and psoriatic arthritis, which are autoimmune diseases, septic arthritis, caused by joint infection; and the more common osteoarthritis, or degenerative joint disease. Arthritis can be caused from ranges and injuries caused by rhythmic motion, sporting activities, overexertion, and falls. Arthritic joints can be sensitive to weather changes. The increased sensitivity is thought to be caused by the affected joints increasing extra nerve being in an attempt to protect the joint from further injury.
- Did you know that there are more than 100 types of arthritis?
- Common arthritis symptoms of inflammation, pain, and stiffness are usually caused by degenerative arthritis.
- Other types of arthritis contain rheumatoid arthritis and gout.
Learn How to stop Gout Pain and Inflammation Do you wake up in the middle of the night, and your big toe feels as if it was on fire. It s swollen, hot and has the feeling were its tender that even the weight of your sheet touching it seems unbearable.In the United States alone over two...
X-Rays Will be the Single Most Useful Tool in Diagnosing Charcot Joints
Bone scans are helpful in the early phases of Charcot joints and are sensitive indicators of hyperemia (increased blood flow to the area of the fracture). Surface skin temperature is the most reliable indicator of the activity of the fractures. Most doctors do not keep the necessary equipment in order to measure skin temperature but merely measure with direct touch to sense the presence or lack of warmth.
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Treatment of Charcot joints The hallmark of treatment of Charcot joints is early diagnosis and prevention. The signs and findings of Charcot joints vary so that each case requires careful evaluation. Treatment of Charcot joints of the feet may include rest, sending your line and non-weight bearing to allow adequate time for fracture healing. Total contact casting or the use of a Charcot Restraint Orthotic Walker (CROW) are popular in stages one and two. The goal is to limit weight bearing to enable progression in order to stage three. This kind of progression can take from several weeks as much as 6 months. Electrical stimulation, or perhaps bone stimulation, is a trendy adjunct to be able to non-weight bearing or sending your line.
Weak Bones Should Not Just be Excused as a Natural Part of Aging
Strong bones begin when they are young. People of all ages can improve their bone health. Bone is connective tissues that contain a hardened matrix of mineral salts as well as collagen fibers. Its cells include osteocytes, which are embedded within lacunae, and the free-roaming osteoblasts and osteoclasts. Bones support body structures, protect internal organs, and in conjunction with muscles facilitate movement; are also involved with cell formation, calcium metabolism, and mineral storage. The bones of an animal are, collectively, known as the skeleton.
Diabetes mellitus Tabes dorsalis (neuropathy caused by syphilis Hansen's Disease (Leprosy) Tumors with the spinal cord Degenerative change of the spinal cord or peripheral nerve Amyloid Familial-hereditary neuropathies including Charcot-Marie Toothe Disease, Hereditary sensory neuropathy and Dejerine-Sottas Illness Pernicious Anemia.
The description of Charcot joints dates back to be able to 1703 when neuropathic osteoarthropathy was first described by W. Musgrave. Charcot is credited for his work in 1868 for describing gait anomalies of patients with syphilis (tabes dorsalis). Jordan, in was the first to describe a relationship of diabetes to neuropathic arthropathy.
Symptoms: The symptoms of Charcot joints vary considering the location and severity of the condition. The first sign is localized edema swelling) of the joint or joints. The edematous area may exhibit increased temperature change. Often, the first noticeable sign in which a patient with advanced peripheral neuropathy will notice is the fact that their shoes have become tight or they will have difficulty appropriate into a pair of shoes that have fit well for some time.
Saltzman, CL, Johnson KA, Goldstein RH, et al: The patellar tendon-bearing brace when used to treat neuropathic arthropathy: a dynamic force monitoring study. Foot Ankle 13: 14, 1992
- Bassett CA, Mitchell SN, Norton L, et al: Repair of non-unions by pulsing electromagnetic fields.
- Acta Orthop Belg 44: 706,
About the Particular Author:Jeffrey a
Oster, DPM, C.Ped is a board certified foot and ankle surgeon. Dr. Oster is also board certified in pedorthics. Doctor. Oster is medical director of Myfootshop.com and is in active practice in Granville, Ohio.
- Arthritis is a group of conditions involving injury to the joints of the body.
- The most common form of arthritis, osteoarthritis is a result of trauma to the joint, an infection of the joint, or age.
Strong Bones Hold Up, Support Us and So are the Structure for Our Muscles
Bones are a storehouse for extremely important minerals needed to live. Strong bones protect the heart, lungs, brain, and other organs from injury. Weak bones often effect in painful and deterioration fractures. Hip cracks are the most damaging type of bone crack and account for almost 300,000 hospitalizations each year.
- Sticha RS, Frascone ST, Werthheimer SJ: Major arthrodesis in patients with neuropathic arthropathy.
- J Foot Ankle Surg 35: Frykberg RG, Osteoarthropathy.
- Clin Podiatric Med Surg 4:351,
- The group proposed by Brodsky in 1992 includes the location of the Charcot joint and it is commonly used in clinical practice today.
- Brodsky's classification is as follows;
The concern in diagnosing this condition is the lack of symptoms that are due to peripheral neuropathy. Peripheral neuropathy makes it impossible for the patient to be able to speak in terms that would be understood by the general population such as 'my ft hurt'. As a result, the physician needs to rely more on testing and less on the history and physical exam.
Type 5 - The forefoot. Charcot joints are often not diagnosed until they generate another problem that impacts a patients normal activities. These may be as simple as an inability to fit into shoes, or as severe as an infected ulceration of the foot. By this stage, the Charcot deformity has in all likelihood progressed to a point where there is massive displacement of the bones and joints along with several displaced fractures.
The most common complicating factor of a Charcot joint of the foot is the prominence that grows on the bottom of the foot, referred to as a 'rocker bottom' foot. This condition occurs as the bones of the arch collapse. In an advanced rocker bottom foot, the inability to feeling pain becomes a complicating factor for the skin. As the bone places more pressure on the skin, the skin begins to ulcerate and becomes contaminated.
The main cause of gout is the clustering of uric acid crystals in the blood vessels, obstructing normal blood flow and leading to inflammation. Due to either excessive production of uric acid in the body or renal insufficiency (sometimes the kidneys are unable to eliminate the surplus of uric acid), uric acid accumulates, crystallizes and deposits in different body areas. Food intake plays a major role in the development of gout. Some foods are usually rich in fat and purine, a substance that is synthesized by the organism into uric acid and therefore may aggravate the symptoms of gout. Smoking and the consumption of alcohol ought to be considerably reduced when suffering from gout, because they factors affect the secretion of uric acid, causing the accumulation within the entire body.
The Development of a Charcot Joint Could be Rapid and Depends Upon Several Variables
Any ability to perceive pain may lead to a more prompt diagnosis due to a patient's concern concerning their abilities to complete an average day. Full loss of deep pain sensation may delay early diagnosis. Charcot joints are easily confused with osteoarthritis, that is handled much less aggressively than a Charcot joint.
Some people who have chronically high blood levels of urate (commonly referred to as uric acid) will go on to develop gout, but not everybody. In fact, up to roughly 2/3 of the population who have higher levels of urate do not become victims of gout. Why? No one really knows for sure. Could for women who live less tolerance for higher levels of uric acid since before menopause their levels are generally much lower? Once again, the jury is out on this one.
- Type 3A - Ankle joint - 9% of all Charcot deformities.
- Type 3B - The posterior calcaneus.
- Type 4 - Multiple instances of the foot and/or ankle.
- People who suffer from gout may experience sudden, unexpected pain episodes that tend to reoccur occasionally.
- This may be a first sign of chronic gout.
- The pain is sometimes more intense during the night in the case of some people who suffer from gout.
- Another type of gout, referred to as pseudogout, occurs due to the accumulation of crystallized calcium in the joints, instead of uric acid.
- The most frequent area of the foot to be effected by a Charcot joint is the middle arch.
- Charcot joints can also develop at the rearfoot and ankle but are much less common.
- The most common cause of Charcot joints of the foot is peripheral neuropathy due to diabetes mellitus.
- Other factors that may contribute to producing neuropathy, and subsequently, Charcot joints include;
- Alcoholic neuropathy Congenital insensitivity to pain Pott's Disease (tuberculosis of the spine)
- Lavery La, Armstrong DG, Walker SC: Therapeutic rates of diabetic foot ulcers associated with midfoot fracture due to Charcot's arthropathy.
- Diabet Med 14:46, 1996
- Type 1 - Lisfrank's joint - 27-60% of all Charcot joint deformities of the feet.
- Type 2 - Chopart's joints and also subtalar joints - 30-35%.
Other factors that may facilitate the development of gout are prolonged treatments with diuretics, earlier surgeries, the presence of certain diseases that affect blood circulation or extreme medical treatments such as radiation treatment.
- Reinherz RP, Cheleuitte ER, Fleischle JG: Identification and treatment of the particular diabetic neuropathic foot.
- J Foot ankle Surg
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- For information and products on natural pain relief and other life-enhancing nutrients please visit his website Alternative Health Supplements.